DDB2 抗体 (AA 260-340)
Our Local Distributor
北京 101111
Quick Overview for DDB2 抗体 (AA 260-340) (ABIN8120908)
抗原
See all DDB2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 260-340
-
原理
- DDB2 Antibody
-
特异性
- DDB2 Polyclonal Antibody detects endogenous levels of protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from human protein . at AA range: 260-340
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-2000 ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
-
别名
- DDB2
-
背景
-
Background: This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
Gene Name: DDB2
Protein Name: DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)
-
基因ID
- 1643
-
UniProt
- Q92466
-
途径
- DNA Damage Repair
抗原
-