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DDB2 抗体 (AA 260-340)

The 兔 多克隆 anti-DDB2 antibody (ABIN8120908) specifically detects DDB2 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN8120908
发货至: 中国
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Quick Overview for DDB2 抗体 (AA 260-340) (ABIN8120908)

抗原

See all DDB2 抗体
DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

适用

  • 80
  • 18
  • 10
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 79
  • 3
兔

克隆类型

  • 55
  • 27
多克隆

标记

  • 35
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This DDB2 antibody is un-conjugated

应用范围

  • 62
  • 34
  • 25
  • 25
  • 24
  • 20
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 13
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 260-340

    原理

    DDB2 Antibody

    特异性

    DDB2 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human protein . at AA range: 260-340

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

    别名

    DDB2

    背景

    Background: This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],

    Gene Name: DDB2

    Protein Name: DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)

    基因ID

    1643

    UniProt

    Q92466

    途径

    DNA Damage Repair
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