CDK6 抗体
Our Local Distributor
北京 101111
Quick Overview for CDK6 抗体 (ABIN8120812)
抗原
See all CDK6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- CDK6 Rabbit mAb
-
特异性
- This antibody detects endogenous levels of CDK6 protein.
-
纯化方法
- The antibody was purified by protein A affinity chromatography.
-
免疫原
- Recombinant protein (or fragment).
-
亚型
- IgG
-
-
-
-
应用备注
- WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid freeze / thaw cycles
-
储存条件
- -20 °C
-
储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
-
-
- CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
-
别名
- CDK6
-
背景
-
Synonyms: Cyclin-dependent kinase 6 (EC 2. 7. 11. 22, Cell division protein kinase 6, Serine/threonine-protein kinase PLSTIRE)
Background: cyclin dependent kinase 6 (CDK6) Homo sapiens The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefS
Gene Name: CDK6 CDKN6
Protein Name: CDK6
-
基因ID
- 1021
-
UniProt
- Q00534
-
途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
-