CDK6 抗体 (AA 280-325)
Our Local Distributor
北京 101111
Quick Overview for CDK6 抗体 (AA 280-325) (ABIN8120811)
抗原
See all CDK6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 280-325
-
原理
- Cdk6 Antibody
-
特异性
- The antibody detects endogenous Cdk6
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthetic peptide from human protein at AA range: 280-325
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-2000,IHC 1:500-200, ELISA 1:10000-20000. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
-
别名
- Cdk6
-
背景
-
Synonyms: Cyclin-dependent kinase 6 (EC 2.7.11.22, Cell division protein kinase 6, Serine/threonine-protein kinase PLSTIRE)
Background: cyclin dependent kinase 6(CDK6) Homo sapiens The protein encoded byThis gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefS
Gene Name: CDK6 CDKN6
Protein Name: Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)
-
基因ID
- 1021
-
UniProt
- Q00534
-
途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
-