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CDK6 抗体 (AA 280-325)

The 兔 多克隆 anti-CDK6 antibody is suitable to detect CDK6 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN8120811
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CDK6 抗体 (AA 280-325) (ABIN8120811)

抗原

See all CDK6 抗体
CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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  • 38
多克隆

标记

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This CDK6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 280-325

    原理

    Cdk6 Antibody

    特异性

    The antibody detects endogenous Cdk6

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthetic peptide from human protein at AA range: 280-325

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:500-200, ELISA 1:10000-20000. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

    别名

    Cdk6

    背景

    Synonyms: Cyclin-dependent kinase 6 (EC 2.7.11.22, Cell division protein kinase 6, Serine/threonine-protein kinase PLSTIRE)

    Background: cyclin dependent kinase 6(CDK6) Homo sapiens The protein encoded byThis gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefS

    Gene Name: CDK6 CDKN6

    Protein Name: Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)

    基因ID

    1021

    UniProt

    Q00534

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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