CDK4 抗体 (pThr172)
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北京 101111
Quick Overview for CDK4 抗体 (pThr172) (ABIN8120808)
抗原
See all CDK4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr172
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原理
- CDK4 (Phospho Thr172) Antibody
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特异性
- This antibody detects endogenous levels of CDK4 (Phospho-Thr172) at Human, Mouse,Rat
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human CDK4 (Phospho-Thr172)
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CDK4 (Cyclin-Dependent Kinase 4 (CDK4))
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别名
- CDK4
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背景
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Synonyms: Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)
Background: cyclin dependent kinase 4(CDK4) Homo sapiens The protein encoded byThis gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008],
Gene Name: CDK4
Protein Name: CDK4 (Phospho-Thr172)
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基因ID
- 1019
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UniProt
- P11802
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
抗原
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