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CBP 抗体

The 兔 单克隆 anti-CBP antibody is suitable to detect CBP in samples from 人, 小鼠 和 大鼠. It has been validated for IHC, WB, IF, ELISA 和 IP.
产品编号 ABIN8120751
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CBP 抗体 (ABIN8120751)

抗原

See all CBP (CREBBP) 抗体
CBP (CREBBP) (CREB Binding Protein (CREBBP))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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单克隆

标记

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This CBP antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

克隆位点

AB2005
  • 原理

    CREBBP Rabbit mAb

    特异性

    This antibody detects endogenous levels of CREBBP protein.

    纯化方法

    The antibody was purified by protein A affinity chromatography.

    免疫原

    Recombinant protein (or fragment).

    亚型

    IgG
  • 应用备注

    WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    CBP (CREBBP) (CREB Binding Protein (CREBBP))

    别名

    CREBBP

    背景

    Synonyms: CREB-binding protein (EC 2.3.1.48)

    Background: CREB binding protein (CREBBP)     Homo sapiens    This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB) , this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS) . Chromosomal translocations invo

    Gene Name: CREBBP CBP

    Protein Name: CREBBP

    基因ID

    1387

    UniProt

    Q92793

    途径

    TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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