Prothrombin 抗体
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北京 101111
Quick Overview for Prothrombin 抗体 (ABIN8120632)
抗原
See all Prothrombin (F2) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Prothrombin Antibody
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特异性
- Prothrombin Polyclonal Antibody detects endogenous levels of Prothrombin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human Prothrombin. AA range 420-470
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
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别名
- Prothrombin
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背景
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Synonyms: F2, Prothrombin, Coagulation factor II
Background: Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],
Gene Name: F2
Protein Name: Prothrombin
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基因ID
- 2147
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UniProt
- P00734
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途径
- Complement System, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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