Claudin 1 抗体 (AA 150-211)
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北京 101111
Quick Overview for Claudin 1 抗体 (AA 150-211) (ABIN8120589)
抗原
See all Claudin 1 (CLDN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 150-211
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原理
- Claudin 1 mouse mAb
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特异性
- This antibody detects endogenous levels of Claudin 1 protein.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 150 - 211 of the human Claudin 1 protein.
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亚型
- IgG
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应用备注
- IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- Claudin 1 (CLDN1)
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别名
- Claudin 1
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背景
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Synonyms: Senescence-associated epithelial membrane protein
Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008],
Gene Name: CLDN1
Protein Name: Claudin 1
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基因ID
- 9076
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UniProt
- O95832
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途径
- Cell-Cell Junction Organization, Hepatitis C
抗原
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