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CTNND1 抗体 (AA 600-700)

The 小鼠 单克隆 anti-CTNND1 antibody is suitable to detect CTNND1 in samples from 人, 小鼠 和 大鼠. It has been validated for IHC.
产品编号 ABIN8120250
发货至: 中国
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北京 101111
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Quick Overview for CTNND1 抗体 (AA 600-700) (ABIN8120250)

抗原

See all CTNND1 抗体
CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

适用

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人, 小鼠, 大鼠

宿主

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  • 51
小鼠

克隆类型

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单克隆

标记

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This CTNND1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

AB1263
  • 抗原表位

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    AA 600-700

    原理

    p120 catenin Mouse mAb (Ready to Use)

    特异性

    The antibody can specifically recognize human p120 catenin protein.

    纯化方法

    The antibody was purified by protein G affinity chromatography.

    免疫原

    A synthetic peptide corresponding to the amino acid region 600 - 700 of the human p120 catenin protein.

    亚型

    IgG
  • 应用备注

    It has been optimized for direct use, requiring no further dilution.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze

    储存条件

    4 °C

    储存方法

    Store at 4°C. Avoid freeze.
  • 抗原

    CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

    别名

    p120 catenin

    背景

    Synonyms: Cadherin associated Src substRate, Cadherin-associated Src substRate, CAS, Catenin (cadherin associated protein) delta 1, Catenin delta 1, Catenin delta, Catenin delta-1, CTND1_HUMAN, CTNND 1, CTNND, CTNND1, delta 1 Catenin, KIAA0384, p120, P120 CAS, p120 catenin, P120 CTN, p120 (cas) , p120 (ctn) , P120CAS, P120CTN

    Background: α- Catenin, β- Catenin, γ- catenin and p120 catenin are members of the connexin family and mediate intercellular adhesion together with E- cadherin. P120 catenin binds to the near membrane region of E- cadherin to form a complex, which is stable and closely linked. In lobular breast cancer, E- cadherin deficiency resulted in the accumulation of p120 catenin in the cytoplasm, while in ductal breast cancer, p120 catenin in the membrane decreased and there was no accumulation of p120 catenin in the cytoplasm. Therefore, it can be used to distinguish lobular carcinoma from ductal carcinoma. Studies have shown that p120 catenin in the cytoplasm of gastric and colon cancer is related to poor adhesion of cancer cells.

    Gene Name: CTNND1

    Protein Name: p120 catenin

    基因ID

    1500

    UniProt

    O60716

    途径

    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
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