Caspase 7 抗体 (AA 160-240)
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Quick Overview for Caspase 7 抗体 (AA 160-240) (ABIN8120238)
抗原
See all Caspase 7 (CASP7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 160-240
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原理
- Caspase-7 Antibody
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特异性
- Caspase-7 Polyclonal Antibody detects endogenous levels of Caspase-7 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from Caspase-7 . at AA range: 160-240
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亚型
- IgG
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应用备注
- WB 1:500-2000, IF 1:50-300, IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
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别名
- Caspase-7
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背景
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Synonyms: CASP7, MCH3, Caspase-7, CASP-7, Apoptotic protease Mch-3, CMH-1, ICE-like apoptotic protease 3, ICE-LAP3
Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],
Gene Name: CASP7
Protein Name: Caspase7
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基因ID
- 840
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UniProt
- P55210
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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