Caspase 2 抗体 (Cleaved-Ala348)
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Quick Overview for Caspase 2 抗体 (Cleaved-Ala348) (ABIN8120230)
抗原
See all Caspase 2 (CASP2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cleaved-Ala348
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原理
- Caspase 2 (p12, Cleaved-Ala348) Antibody
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特异性
- This antibody detects endogenous levels of Human Caspase 2 (p12, Cleaved-Ala348, protein was cleaved amino acid sequence between 347-348)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human Caspase 2 (p12, Cleaved-Ala348)
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亚型
- IgG
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anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 334-452) antibody
CASP2 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 153-452) antibodyCASP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) antibodyKD Validated CASP2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4375 unconjugated Recombinant Antibody
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) antibodyKD Validated CASP2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3305 unconjugated Recombinant Antibody
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 170-325) antibodyCASP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 198-226) antibodyCASP2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18402 unconjugated
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) antibodyCASP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 3D4 unconjugated Recombinant Antibody
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 198-226) antibodyCASP2 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (C-Term) antibodyCASP2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (N-Term) antibodyCASP2 适用: 人, 小鼠 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
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别名
- Caspase 2
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背景
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Synonyms: Caspase-2 (CASP-2, EC 3.4.22.55, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1) [Cleaved into: Caspase-2 subunit p18, Caspase-2 subunit p13, Caspase-2 subunit p12]
Background: alternative products:Isoforms differ in the N- and C-termini,catalytic activity:Strict requirement for an Asp residue at P1, with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-|-.,function:Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.,PTM:The mature protease can process its own propeptide, but not that of other caspases.,similarity:Belongs to the peptidase C14A family.,similarity:Contains 1 CARD domain.,subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a p18 subunit and a p12 subunit. Interacts with LRDD.,tissue specificity:Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.,
Gene Name: CASP2 ICH1 NEDD2
Protein Name: Caspase2
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基因ID
- 835
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UniProt
- P42575
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway
抗原
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