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Caspase 10 抗体 (Cleaved-Ala416)

The 兔 多克隆 anti-Caspase 10 antibody is suitable to detect Caspase 10 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN8120226
发货至: 中国
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Quick Overview for Caspase 10 抗体 (Cleaved-Ala416) (ABIN8120226)

抗原

See all Caspase 10 (CASP10) 抗体
Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

适用

人, 小鼠, 大鼠

宿主

  • 114
  • 4
  • 2
  • 1
兔

克隆类型

  • 88
  • 33
多克隆

标记

  • 48
  • 9
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  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
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  • 1
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This Caspase 10 antibody is un-conjugated

应用范围

  • 81
  • 55
  • 36
  • 33
  • 22
  • 21
  • 17
  • 14
  • 14
  • 8
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 16
    • 15
    • 12
    • 9
    • 8
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 1
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    • 1
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    • 1
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    Cleaved-Ala416

    原理

    Caspase 10 (p12, Cleaved-Ala416) Antibody

    特异性

    This antibody detects endogenous levels of Human Caspase 10 (p12, Cleaved-Ala416, protein was cleaved amino acid sequence between 415-416)

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

    免疫原

    Synthesized peptide derived from human Caspase 10 (p12, Cleaved-Ala416)

    亚型

    IgG
  • 应用备注

    WB 1:1000-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

    别名

    Caspase 10

    背景

    Synonyms: Caspase-10 (CASP-10, EC 3.4.22.63, Apoptotic protease Mch-4, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE-like apoptotic protease 4) [Cleaved into: Caspase-10 subunit p23/17, Caspase-10 subunit p12]

    Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011],

    Gene Name: CASP10 MCH4

    Protein Name: Caspase10

    基因ID

    843

    UniProt

    Q92851

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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