CAMK2A 抗体
Our Local Distributor
北京 101111
Quick Overview for CAMK2A 抗体 (ABIN8120133)
抗原
See all CAMK2A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- CaMKII α Rabbit mAb
-
特异性
- This antibody detects endogenous levels of CaMKII α protein.
-
纯化方法
- The antibody was purified by protein A affinity chromatography.
-
免疫原
- Recombinant protein (or fragment).
-
亚型
- IgG
-
-
-
-
应用备注
- WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid freeze / thaw cycles
-
储存条件
- -20 °C
-
储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
-
-
- CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
-
别名
- CaMKII alpha
-
背景
-
Synonyms: Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)
Background: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca (2+) /calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2018]
Gene Name: CAMK2A CAMKA KIAA0968
Protein Name: CaMKII α
-
基因ID
- 815
-
UniProt
- Q9UQM7
-
途径
- WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction
抗原
-