BMP4 抗体 (AA 261-310)
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Quick Overview for BMP4 抗体 (AA 261-310) (ABIN8120011)
抗原
See all BMP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 261-310
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原理
- BMP-4 Antibody
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特异性
- This antibody detects endogenous levels of Human BMP-4
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human BMP-4 AA range: 261-310
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亚型
- IgG
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应用备注
- WB 1:1000-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
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别名
- BMP-4
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背景
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Synonyms: Bone morphogenetic protein 4 (BMP-4, Bone morphogenetic protein 2B, BMP-2B)
Background: disease:Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6) [MIM:607932], also known as microphthalmia and pituitary anomalies or microphthalmia with brain and digit developmental anomalies. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. MCOPS6 is characterized by microphthalmia/anophthalmia associated with facial, genital, skeletal, neurologic and endocrine anomalies.,function:Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair.,online information:Bone morphogenetic protein 4 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer, disulfide-linked (By similarity). Interacts with GREM2 (By similarity) and SOSTDC1. Part of a complex consisting of TWSG1 and CHRD.,tissue specificity:Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.,
Gene Name: BMP4 BMP2B DVR4
Protein Name: BMP-4
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基因ID
- 652
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UniProt
- P12644
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途径
- Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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