BAG4 抗体
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北京 101111
Quick Overview for BAG4 抗体 (ABIN8119966)
抗原
See all BAG4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Bag-4 Antibody
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特异性
- Bag-4 Polyclonal Antibody detects endogenous levels of Bag-4 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the C-terminal region of human Bag-4.
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亚型
- IgG
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anti-BCL2-Associated Athanogene 4 (BAG4) (AA 6-185) antibody
BAG4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (AA 1-457) antibodyBAG4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (AA 1-457) antibodyBAG4 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (Internal Region) antibodyVerified BAG4 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (N-Term) antibodyBAG4 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (C-Term) antibodyBAG4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (C-Term) antibodyBAG4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (AA 1-457) antibodyBAG4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (C-Term) antibodyBAG4 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (AA 226-275) antibodyBAG4 适用: 人, 犬, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- BAG4 (BCL2-Associated Athanogene 4 (BAG4))
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别名
- Bag-4
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背景
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Synonyms: BAG4, SODD, BAG family molecular chaperone regulator 4, BAG-4, Bcl-2-associated athanogene 4, Silencer of death domains
Background: The protein encoded byThis gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct
Gene Name: BAG4
Protein Name: BAG family molecular chaperone regulator 4
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基因ID
- 9530
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UniProt
- O95429
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途径
- Regulation of Actin Filament Polymerization
抗原
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