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BBS7 抗体 (AA 85-135)

The 兔 多克隆 anti-BBS7 antibody (ABIN8119957) specifically detects BBS7 in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN8119957
发货至: 中国
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Quick Overview for BBS7 抗体 (AA 85-135) (ABIN8119957)

抗原

See all BBS7 抗体
BBS7 (Bardet-Biedl Syndrome 7 (BBS7))

适用

  • 29
  • 4
  • 2
人, 小鼠

宿主

  • 25
  • 3
  • 1
兔

克隆类型

  • 27
  • 2
多克隆

标记

  • 20
  • 3
  • 2
  • 2
  • 1
  • 1
This BBS7 antibody is un-conjugated

应用范围

  • 22
  • 15
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 85-135

    原理

    BBS7 Antibody

    特异性

    This antibody detects endogenous levels of BBS7 at Human/Mouse

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human BBS7 AA range: 85-135

    亚型

    IgG
  • 应用备注

    WB 1:500-2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    BBS7 (Bardet-Biedl Syndrome 7 (BBS7))

    别名

    BBS7

    背景

    Background: This gene encodes one of eight proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6, BBS10, and BBS12) and CCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome, a genetic disorder whose symptoms include obesity, retinal degeneration, polydactyly and nephropathy, however, mutations in this gene and the BBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq, Oct 2014],

    Gene Name: BBS7 BBS2L1

    Protein Name: BBS7

    基因ID

    55212

    UniProt

    Q8IWZ6

    途径

    Hedgehog Signaling
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