AIF 抗体
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北京 101111
Quick Overview for AIF 抗体 (ABIN8119777)
抗原
See all AIF (AIFM1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- AIF-M1 Rabbit mAb
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特异性
- This antibody detects endogenous levels of AIF-M1 protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 131-230) antibody
AIFM1 适用: 人 WB, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) antibodyAIFM1 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4E7 unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 103-322) antibodyAIFM1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (C-Term) antibodyVerified AIFM1 适用: 人, 大鼠, 小鼠, Pig WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 334-613) antibodyAIFM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) antibodyKD Validated AIFM1 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 25GB2810 unconjugated Recombinant Antibody
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (C-Term) antibodyAIFM1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 183-195) antibodyVerified AIFM1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 70-98), (N-Term) antibodyAIFM1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB22966 unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (C-Term) antibodyAIFM1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, FACS 宿主: 小鼠 Monoclonal 2I5 unconjugated
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应用备注
- WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
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别名
- AIF-M1
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背景
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Synonyms: AIFM1, AIF, PDCD8, Apoptosis-inducing factor 1, mitochondrial, Programmed cell death protein 8
Background: This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6) , a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4) , a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and mental retardation. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome
Gene Name: AIFM1
Protein Name: AIF-M1
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基因ID
- 9131
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UniProt
- O95831
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途径
- Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect
抗原
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