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ACTN1 抗体 (AA 1-80)

The 兔 多克隆 anti-ACTN1 antibody (ABIN8119525) specifically detects ACTN1 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8119525
发货至: 中国
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Quick Overview for ACTN1 抗体 (AA 1-80) (ABIN8119525)

抗原

See all ACTN1 抗体
ACTN1 (Actinin, alpha 1 (ACTN1))

适用

  • 60
  • 24
  • 21
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 49
  • 10
  • 1
兔

克隆类型

  • 50
  • 10
多克隆

标记

  • 39
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ACTN1 antibody is un-conjugated

应用范围

  • 40
  • 26
  • 21
  • 15
  • 9
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 10
    • 9
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-80

    原理

    Actinin-α1 Antibody

    特异性

    Actinin-α1 Polyclonal Antibody detects endogenous levels of Actinin-α1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from Actinin-alpha1 . at AA range: 1-80

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    ACTN1 (Actinin, alpha 1 (ACTN1))

    别名

    Actinin-alpha1

    背景

    Synonyms: ACTN1, Alpha-actinin-1, Alpha-actinin cytoskeletal isoform, F-actin cross-linking protein, Non-muscle alpha-actinin-1

    Background: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

    Gene Name: ACTN1

    Protein Name: Alpha-actinin-1

    基因ID

    87

    UniProt

    P12814

    途径

    Cell-Cell Junction Organization
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