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- 抗原 See all ACTN1 抗体
- ACTN1 (Actinin, alpha 1 (ACTN1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ACTN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Whole Mount) (IHC (wm))
- 交叉反应
- 人, 小鼠, 大鼠, 斑马鱼
- 产品特性
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Rabbit Polyclonal antibody to alpha Actinin 1 (actinin, alpha 1)
alpha Actinin 1 antibody [N2N3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human alpha Actinin 1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product ACTN1 Primary Antibody
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anti-Actinin, alpha 1 (ACTN1) (AA 1-330) antibody
ACTN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) antibodyACTN1 适用: 人, 小鼠, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) antibodyACTN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 543-639) antibodyACTN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Actinin, alpha 1 (ACTN1) antibodyACTN1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 28-260) antibodyACTN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 1-204) antibodyACTN1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 543-639) antibodyACTN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) antibodyACTN1 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 1-892) antibodyACTN1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: NIH-3T3 , 293T , A431 , HeLa , HepG2 , PC-12 , Rat2 , rat brain
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.09 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- ACTN1 (Actinin, alpha 1 (ACTN1))
- 别名
- actinin alpha 1 (ACTN1 产品)
- 别名
- ACTN1 antibody, actinin antibody, BDPLT15 antibody, 3110023F10Rik antibody, Actn1a antibody, actinin alpha 1 antibody, actinin, alpha 1 antibody, actinin alpha 1 L homeolog antibody, ACTN1 antibody, actn1 antibody, Actn1 antibody, actn1.L antibody
- 背景
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Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Cytoplasm , cytoskeleton , myofibril , sarcomere , Z-disk - 分子量
- 103 kDa
- 基因ID
- 87
- UniProt
- P12814
- 途径
- Cell-Cell Junction Organization
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