OGG1 抗体
Our Local Distributor
北京 101111
Quick Overview for OGG1 抗体 (ABIN8119475)
抗原
See all OGG1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- OGG1 Antibody
-
特异性
- OGG1 Polyclonal Antibody detects endogenous levels of protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from part region of human protein
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-2000 ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
-
别名
- OGG1
-
背景
-
Background: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008],
Gene Name: OGG1 MMH MUTM OGH1
Protein Name: N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-)DNA-(apurinic or apyrimidinic site) lyase (AP lyase) (EC 4.2.99.18)]
-
基因ID
- 4968
-
UniProt
- O15527
-
途径
- DNA Damage Repair
抗原
-