WASF1 抗体
Our Local Distributor
北京 101111
Quick Overview for WASF1 抗体 (ABIN8115785)
抗原
See all WASF1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- WASF1 Antibody
-
序列
- TPYRDDGKEG LKFYTNPSYF FDLWKEKMLQ DTEDKRKEKR KQKQKNLDRP
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%, Zebrafish: 92%
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the following sequence TPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRP
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63994-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- WASF1 (WAS Protein Family, Member 1 (WASF1))
-
别名
- WASF1
-
背景
-
Background Information: The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Gene Name: WAS protein family, member 1
Alternative Symbols: WAVE, SCAR1, WAVE1, NEDALVS
Protein Name: Wiskott-Aldrich syndrome protein family member 1
-
分子量
- 62 kDa
-
基因ID
- 8936
-
NCBI登录号
- NP_003922
-
UniProt
- Q92558
-
途径
- RTK signaling, Regulation of Actin Filament Polymerization
抗原
-