STRADB 抗体 (C-Term)
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北京 101111
Quick Overview for STRADB 抗体 (C-Term) (ABIN8112916)
抗原
See all STRADB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- STRADB Antibody - C-terminal region
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序列
- GTHTVNSDRL HTPSSKTFSP AFFSLVQLCL QQDPEKRPSA SSLLSHVFFK
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human STRAB
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49234-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- STRADB (STE20-Related Kinase Adaptor beta (STRADB))
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别名
- STRADB
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背景
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Background Information: This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Name: STE20-related kinase adaptor beta
Alternative Symbols: PAPK, ILPIP, ILPIPA, ALS2CR2, CALS-21, PRO1038
Protein Name: STE20-related kinase adapter protein beta
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分子量
- 41kDa
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基因ID
- 55437
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UniProt
- Q9C0K7
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途径
- AMPK Signaling
抗原
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