ARHGEF3 抗体 (N-Term)
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北京 101111
Quick Overview for ARHGEF3 抗体 (N-Term) (ABIN8110521)
抗原
See all ARHGEF3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- ARHGEF3 Antibody - N-terminal region
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序列
- VKPLSRVTSL ANLIPPVKAT PLKRFSQTLQ RSISFRSESR PDILAPRPWS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human ARHG3
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anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 211-240) antibody
ARHGEF3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB27451 unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 287-526) antibodyARHGEF3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) antibodyARHGEF3 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 33-142) antibodyARHGEF3 适用: 人 ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (C-Term) antibodyARHGEF3 适用: 人, 猴 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (C-Term) antibodyARHGEF3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 287-526) antibodyARHGEF3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (C-Term) antibodyARHGEF3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 1-324) antibodyARHGEF3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57339-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
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别名
- ARHGEF3
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背景
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Background Information: Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Name: Rho guanine nucleotide exchange factor 3
Alternative Symbols: GEF3, STA3, XPLN
Protein Name: rho guanine nucleotide exchange factor 3
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分子量
- 57kDa
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基因ID
- 50650
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UniProt
- Q9NR81
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途径
- Neurotrophin Signaling Pathway
抗原
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