GFR 抗体 (Middle Region)
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北京 101111
Quick Overview for GFR 抗体 (Middle Region) (ABIN8109980)
抗原
See all GFR (RAPGEF5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- RAPGEF5 Antibody - middle region
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序列
- GMHRRHTVDE YSPQKKNKAL FHQFSLKENW LQHRGTVTET EEIFCHVYIT
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human RPGF5
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anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) antibody
RAPGEF5 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (AA 201-444) antibodyRAPGEF5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (AA 1-444) antibodyRAPGEF5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (AA 1-444) antibodyRAPGEF5 适用: 人 WB 宿主: 小鼠 Monoclonal 2E4 unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (AA 529-555), (C-Term) antibodyRAPGEF5 适用: 人 WB 宿主: 兔 Polyclonal RB36938 unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (C-Term) antibodyRAPGEF5 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (N-Term) antibodyRAPGEF5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75290-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))
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别名
- RAPGEF5
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背景
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Background Information: Members of the RAS (see HRAS, MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]
Gene Name: Rap guanine nucleotide exchange factor 5
Alternative Symbols: GFR, REPAC, MR-GEF
Protein Name: rap guanine nucleotide exchange factor 5
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分子量
- 48kDa
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基因ID
- 9771
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UniProt
- Q92565
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途径
- RTK signaling, Neurotrophin Signaling Pathway, Hepatitis C
抗原
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