PRKD3 抗体 (Middle Region)
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北京 101111
Quick Overview for PRKD3 抗体 (Middle Region) (ABIN8109314)
抗原
See all PRKD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- PRKD3 Antibody - middle region
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序列
- GEVTFNGEPS SLGTDTDIPM DIDNNDINSD SSRGLDDTEE PSPPEDKMFF
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human KPCD3
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75491-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PRKD3 (Protein Kinase D3 (PRKD3))
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别名
- PRKD3
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背景
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Background Information: This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain. The C-terminal region contains the catalytic domain and is distantly related to calcium-regulated kinases. Catalytic activity of this enzyme promotes its nuclear localization. This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation, growth regulation of breast and prostate cancer cells, and vesicle trafficking.
Gene Name: protein kinase D3
Alternative Symbols: EPK2, PKD3, PRKCN, PKC-NU, nPKC-NU
Protein Name: serine/threonine-protein kinase D3
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分子量
- 97kDa
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基因ID
- 23683
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NCBI登录号
- XP_005264294
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UniProt
- O94806
抗原
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