NLRP1 抗体 (Middle Region)
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北京 101111
Quick Overview for NLRP1 抗体 (Middle Region) (ABIN8106572)
抗原
See all NLRP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- NLRP1 Antibody - middle region
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序列
- LCSLAAEGIW QKKTLFSPDD LRKHGLDGAI ISTFLKMGIL QEHPIPLSYS
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预测反应
- Cow: 85%, Dog: 100%, Horse: 79%, Human: 100%
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NLRP1
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anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) (AA 323-372) antibody
NLRP1 适用: 人, 小鼠, Cow, 犬, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) (C-Term) antibodyNLRP1 适用: 人 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) antibodyNLRP1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) (AA 2-25), (N-Term) antibodyNLRP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) (N-Term) antibodyNLRP1 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) (AA 1-146) antibodyNLRP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) (AA 1-1429) antibodyNLRP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54479-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
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别名
- NLRP1
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背景
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Background Information: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
Gene Name: NLR family pyrin domain containing 1
Alternative Symbols: NAC, JRRP, MSPC, AIADK, CARD7, CIDED, NALP1, SLEV1, DEFCAP, PP1044, VAMAS1, CLR17.1, DEFCAP-L/S
Protein Name: NACHT, LRR and PYD domains-containing protein 1
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分子量
- 157 kDa
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基因ID
- 22861
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NCBI登录号
- NP_001028225
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UniProt
- Q9C000
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途径
- Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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