KSR2 抗体 (N-Term)
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北京 101111
Quick Overview for KSR2 抗体 (N-Term) (ABIN8103917)
抗原
See all KSR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- KSR2 Antibody - N-terminal region
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序列
- LQQCELVQNM IDLSISNLEG LRTKCATSND LTQKEIRTLE SKLVKYFSRQ
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预测反应
- Cow: 100%, Dog: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human KSR2
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anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibody
KSR2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1G4 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibodyKSR2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6C9 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 603-638), (C-Term) antibodyKSR2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB09886 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 159-296) antibodyKSR2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) antibodyKSR2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibodyKSR2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (Internal Region) antibodyKSR2 适用: 人, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal AFfirm8389 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (Internal Region) antibodyKSR2 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (Ile694) antibodyKSR2 适用: 人, 小鼠 WB, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibodyKSR2 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 6F12 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62199-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- KSR2 (Kinase Suppressor of Ras 2 (KSR2))
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别名
- KSR2
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背景
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Background Information: Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
Gene Name: kinase suppressor of ras 2
Protein Name: Kinase suppressor of Ras 2
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分子量
- 108 kDa
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基因ID
- 283455
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UniProt
- Q6VAB6
抗原
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