Recombinant CKB 抗体 (full length)
Our Local Distributor
北京 101111
Quick Overview for Recombinant CKB 抗体 (full length) (ABIN8093101)
抗原
See all CKB 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
抗原表位
- full length
-
原理
- CKB Antibody / Creatine kinase B (azide and preservative free)
-
免疫原
- Recombinant full-length human CKB protein was used as the immunogen for the CKB/Creatine kinase B-type antibody.
-
亚型
- IgG, kappa
-
-
anti-Creatine Kinase, Brain (CKB) antibody
KD Validated CKB 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB4350 unconjugated Recombinant Antibody
anti-Creatine Kinase, Brain (CKB) antibodyCKB 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Brain (CKB) antibodyKD Validated CKB 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB4355 unconjugated Recombinant Antibody
anti-Creatine Kinase, Brain (CKB) (AA 66-179) antibodyCKB 适用: 人, 小鼠 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Brain (CKB) (AA 11-367) antibodyCKB 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal D3 unconjugated
anti-Creatine Kinase, Brain (CKB) (AA 2-270) antibodyCKB 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Brain (CKB) antibodyKO Validated CKB 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2265 unconjugated Recombinant Antibody
anti-Creatine Kinase, Brain (CKB) antibodyKD Validated CKB 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB7005 unconjugated
anti-Creatine Kinase, Brain (CKB) (AA 7-381) antibodyCKB 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Brain (CKB) antibodyCKB 适用: 人 IHC, ELISA, FACS, IF 宿主: 小鼠 Monoclonal 2ba6 unconjugated
-
-
应用备注
-
1. Optimal dilution of the CKB/Creatine kinase B-type antibody should be determined by the researcher.
2. This CKB/Creatine kinase B-type antibody is recombinantly produced by expression in human HEK293 cells. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- CKB/Creatine kinase B-type antibody with sodium azide - store at 2 to 8oC, antibody without sodium azide - store at -20 to -80oC.
-
-
- CKB (Creatine Kinase, Brain (CKB))
-
别名
- CKB
-
背景
-
CKB antibody targets Creatine kinase B-type, a cytosolic enzyme encoded by the CKB gene that catalyzes the reversible transfer of a phosphate group between ATP and creatine, forming phosphocreatine and ADP. Creatine kinase B-type plays a central role in cellular energy homeostasis by buffering and rapidly regenerating ATP in cells with high and fluctuating energy demands. This enzyme represents the brain-type creatine kinase isoform and is widely expressed in neuronal tissues, glial cells, and other cell types with active energy metabolism. CKB antibody is therefore commonly applied in research focused on energy transfer systems, phosphagen metabolism, and cellular bioenergetics.
Creatine kinase B-type exists primarily as a homodimer but can also form heterodimers with the muscle-type creatine kinase subunit, giving rise to the CK-MB isoenzyme. The protein belongs to the creatine kinase family and contains conserved catalytic domains required for creatine and nucleotide binding. In addition to strong expression in the nervous system, CKB has been reported in epithelial tissues, endocrine organs, and proliferative cell populations, supporting its broader role in cellular metabolism beyond the brain. Clone CKBB/8295R is designed to recognize Creatine kinase B-type for research use in studies examining cellular energy dynamics and creatine kinase system regulation.
Altered expression of Creatine kinase B-type has been associated with neurological injury, neurodegenerative disease, and metabolic stress conditions. Changes in CKB levels have also been investigated in cancer biology, where shifts in cellular energy metabolism are a hallmark feature of tumor progression. Because the creatine kinase system is closely linked to ATP availability, redox balance, and cell survival, CKB remains an important research target in studies of neuronal health, metabolic adaptation, and disease-associated bioenergetic remodeling. Clone CKBB/8295R provides a tool for examining Creatine kinase B-type expression and distribution in experimental systems relevant to cellular metabolism and energy-dependent biological processes.
This Creatine Kinase B Antibody is part of a broader < a href=../creatine-kinase-b-antibody-ckb>Creatine Kinase B antibody panel offered by NSJ Bioreagents. -
UniProt
- P12277
抗原
-
