电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Recombinant CKB 抗体 (full length)

The 兔 单克隆 anti-CKB antibody (Clone CKBB-8295R) (ABIN8093100) specifically detects CKB in WB 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN8093100
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CKB 抗体 (full length) (ABIN8093100)

抗原

See all CKB 抗体
CKB (Creatine Kinase, Brain (CKB))

抗体类型

Recombinant Antibody

适用

  • 162
  • 99
  • 87
  • 35
  • 33
  • 12
  • 7
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
人

宿主

  • 114
  • 69
  • 1
兔

克隆类型

  • 104
  • 79
单克隆

标记

  • 111
  • 21
  • 10
  • 5
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CKB antibody is un-conjugated

应用范围

  • 131
  • 57
  • 52
  • 38
  • 35
  • 29
  • 25
  • 14
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

CKBB-8295R
  • 抗原表位

    • 35
    • 13
    • 12
    • 8
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    原理

    CKB Antibody / Creatine kinase B

    免疫原

    Recombinant full-length human CKB protein was used as the immunogen for the CKB/Creatine kinase B-type antibody.

    亚型

    IgG, kappa
  • 应用备注

    1. Optimal dilution of the CKB/Creatine kinase B-type antibody should be determined by the researcher.

    2. This CKB/Creatine kinase B-type antibody is recombinantly produced by expression in human HEK293 cells.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.05 % BSA, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    CKB/Creatine kinase B-type antibody with sodium azide - store at 2 to 8oC, antibody without sodium azide - store at -20 to -80oC.
  • 抗原

    CKB (Creatine Kinase, Brain (CKB))

    别名

    CKB

    背景

    CKB antibody targets Creatine kinase B-type, a cytosolic enzyme encoded by the CKB gene that catalyzes the reversible transfer of a phosphate group between ATP and creatine, forming phosphocreatine and ADP. Creatine kinase B-type plays a central role in cellular energy homeostasis by buffering and rapidly regenerating ATP in cells with high and fluctuating energy demands. This enzyme represents the brain-type creatine kinase isoform and is widely expressed in neuronal tissues, glial cells, and other cell types with active energy metabolism. CKB antibody is therefore commonly applied in research focused on energy transfer systems, phosphagen metabolism, and cellular bioenergetics.

    Creatine kinase B-type exists primarily as a homodimer but can also form heterodimers with the muscle-type creatine kinase subunit, giving rise to the CK-MB isoenzyme. The protein belongs to the creatine kinase family and contains conserved catalytic domains required for creatine and nucleotide binding. In addition to strong expression in the nervous system, CKB has been reported in epithelial tissues, endocrine organs, and proliferative cell populations, supporting its broader role in cellular metabolism beyond the brain. Clone CKBB/8295R is designed to recognize Creatine kinase B-type for research use in studies examining cellular energy dynamics and creatine kinase system regulation.

    Altered expression of Creatine kinase B-type has been associated with neurological injury, neurodegenerative disease, and metabolic stress conditions. Changes in CKB levels have also been investigated in cancer biology, where shifts in cellular energy metabolism are a hallmark feature of tumor progression. Because the creatine kinase system is closely linked to ATP availability, redox balance, and cell survival, CKB remains an important research target in studies of neuronal health, metabolic adaptation, and disease-associated bioenergetic remodeling. Clone CKBB/8295R provides a tool for examining Creatine kinase B-type expression and distribution in experimental systems relevant to cellular metabolism and energy-dependent biological processes.

    This Creatine Kinase B Antibody is part of a broader < a href=../creatine-kinase-b-antibody-ckb>Creatine Kinase B antibody panel offered by NSJ Bioreagents.

    UniProt

    P12277
You are here: