Recombinant CEACAM6 抗体
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北京 101111
Quick Overview for Recombinant CEACAM6 抗体 (ABIN8093035)
抗原
See all CEACAM6 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CEACAM6 Antibody / Carcinoembryonic antigen-related cell adhesion molecule 6 (azide and preservative free)
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免疫原
- Recombinant CEACAM6 protein was used as the immunogen for the CEACAM6/Carcinoembryonic antigen-related cell adhesion molecule 6 antibody.
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亚型
- IgG, kappa
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anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6) antibody
CEACAM6 适用: 人 WB, ELISA, FACS, cELISA, IHC (fro) 宿主: 小鼠 Monoclonal 9A6 unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6) antibodyCEACAM6 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6) (AA 156-265) antibodyCEACAM6 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6) antibodyCEACAM6 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6) (AA 216-265) antibodyCEACAM6 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6) (Internal Region) antibodyCEACAM6 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6) (AA 35-320) antibodyCEACAM6 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6) antibodyCEACAM6 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB1595 unconjugated Recombinant Antibody
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6) antibody (PE)CEACAM6 适用: 人 FACS 宿主: 小鼠 Monoclonal B6-2 PE
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6) antibodyCEACAM6 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal B6-2 unconjugated
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应用备注
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1. Optimal dilution of the CEACAM6/Carcinoembryonic antigen-related cell adhesion molecule 6 antibody should be determined by the researcher.
2. This CEACAM6/Carcinoembryonic antigen-related cell adhesion molecule 6 antibody is recombinantly produced by expression in CHO cells. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- CEACAM6/Carcinoembryonic antigen-related cell adhesion molecule 6 antibody with sodium azide - store at 2 to 8oC, antibody without sodium azide - store at -20 to -80oC.
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- CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))
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别名
- CEACAM6
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背景
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CEACAM6 antibody (clone CEACAM6/13371R) targets Carcinoembryonic Antigen Related Cell Adhesion Molecule 6, a glycosylphosphatidylinositol-anchored cell surface glycoprotein encoded by the human CEACAM6 gene. CEACAM6, also widely referred to as CD66c in immunology literature, is a member of the carcinoembryonic antigen related cell adhesion molecule family involved in intercellular adhesion and immune regulation. CEACAM6 antibody is commonly used in studies of epithelial biology, tumor progression, and inflammatory signaling because CEACAM6 expression is frequently elevated in multiple carcinomas.
CEACAM6 is localized to the plasma membrane via a GPI anchor and mediates homophilic and heterophilic cell-cell interactions. In normal tissues, CEACAM6 is expressed on granulocytes and certain epithelial cells, including those of the gastrointestinal and respiratory tracts. Overexpression of CEACAM6 has been reported in colorectal, pancreatic, gastric, breast, and lung cancers, where it has been associated with tumor cell adhesion, invasion, and resistance to apoptosis. CEACAM6 antibody clone CEACAM6/13371R supports detection of CEACAM6 expression in epithelial tumors and immune cell populations in research applications.
Functionally, CEACAM6 participates in signaling pathways that influence cell survival, proliferation, and metastatic potential. Increased CEACAM6 expression has been linked to enhanced tumor cell motility and reduced anoikis sensitivity, contributing to cancer progression. Because of its cell surface localization and tumor-associated overexpression, CEACAM6 antibody is frequently applied in cancer biology and translational oncology research.
Structurally, CEACAM6 contains immunoglobulin-like extracellular domains characteristic of the CEACAM family and lacks a transmembrane domain due to its GPI anchorage. A CEACAM6 antibody such as clone CEACAM6/13371R is suitable for detecting CEACAM6 expression in epithelial tissues and tumor specimens in research settings. -
UniProt
- P40199
抗原
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