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Desmin 抗体 (pThr76, pThr77)

This anti-Desmin antibody is a 兔 多克隆 antibody detecting Desmin in ELISA 和 FACS. Suitable for 人.
产品编号 ABIN757837
发货至: 中国

Quick Overview for Desmin 抗体 (pThr76, pThr77) (ABIN757837)

抗原

See all Desmin (DES) 抗体
Desmin (DES)

适用

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宿主

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克隆类型

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多克隆

标记

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This Desmin antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    pThr76, pThr77

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human DES around the phosphorylation site of Thr76/Thr77

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Desmin (DES)

    别名

    Desmin +

    背景

    Synonyms: Desmin phospho T76/77, Desmin phospho Thr76/Thr77, Desmin phospho Thr76+Thr77, p-Desmin Thr76/Thr77, CMD1I, CSM1, CSM2, DES, FLJ12025, FLJ39719, FLJ41013, FLJ41793, Intermediate filament protein, OTTHUMP00000064865, DESM_HUMAN, Desmin, FLJ12025, FLJ39719, FLJ41013, FLJ41793.

    Background: filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z line structures. Defects in Desmin are the cause of desmin related cardio skeletal myopathy (CSM) also known as desmin related myopathy (DRM). CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, arrhythmias, restrictive heart failure, and by intracytoplasmic accumulation of desmin reactive deposits in cardiac and skeletal muscle cells. A desmin related myopathy can have a distal onset, it is then known as hereditary distal myopathy (HDM). Defects in Desmin are also the cause of dilated cardiomyopathy type 1I (CMD1I). CMD1I is an autosomal form of dilated cardiomyopathy characterized by ventricular dilatation and impaired systolic function. Antidesmin are useful in identification of tumours of myogenic origin.

    基因ID

    1674
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