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DNMT1 抗体 (pSer154)

Cited in 1 publication. This 兔 多克隆 anti-DNMT1 antibody specifically detects DNMT1 in ELISA, IP, FACS, IHC (p), IF (p), IF (cc) 和 IHC (fro). The antibody is reactive with 人 samples.
产品编号 ABIN757717
发货至: 中国
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Quick Overview for DNMT1 抗体 (pSer154) (ABIN757717)

抗原

See all DNMT1 抗体
DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

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多克隆

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This DNMT1 antibody is un-conjugated

应用范围

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ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    pSer154

    交叉反应

    预测反应

    Mouse,Dog,Cow,Sheep,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human Dnmt1 around the phosphorylation site of Ser153

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    IP(1-2 μg)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Tan, Xu, Zeisberg, Zeisberg: "High inorganic phosphate causes DNMT1 phosphorylation and subsequent fibrotic fibroblast activation." in: Biochemical and biophysical research communications, Vol. 472, Issue 3, pp. 459-64, (2016) (PubMed).

  • 抗原

    DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

    别名

    Dnmt1

    背景

    Synonyms: Dnmt1phospho S154, Dnmt1 phospho Ser154, p-Dnmt1 Ser154, AIM, CXXC finger protein 9, CXXC-type zinc finger protein 9, CXXC9, DNA cytosine 5 methyltransferase 1, DNA cytosine-5-methyltransferase 1, DNA methyltransferase 1, DNA methyltransferase HsaI, DNA methyltransferase M.HsaI., DNA MTase, DNA MTase HsaI, DNMT 1, DNMT, Dnmt1, Dnmt1, DNMT1_HUMAN, Dnmt1o, FLJ16293, HSN1E, M.HsaI, MCMT, Met1, MGC104992, mMmul, MommeD2.

    Background: DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].

    基因ID

    1786

    途径

    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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