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Vitronectin 抗体

The Human 单克隆 anti-Vitronectin antibody is suitable to detect Vitronectin in samples from 人. It has been validated for WB, IHC, ELISA 和 AP.
产品编号 ABIN8065533
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Vitronectin 抗体 (ABIN8065533)

抗原

See all Vitronectin (VTN) 抗体
Vitronectin (VTN)

适用

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宿主

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Human

克隆类型

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单克隆

标记

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This Vitronectin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Affinity Purification (AP)

质量等级

Carrier-free

克隆位点

HV2
  • 原理

    Anti-Vitronectin Antibody

    特异性

    Vitronectin (human). The epitope is located in the connecting region. Binding can be competed selectively by a peptide comprising aa 121-133.

    预测反应

    Human

    纯化方法

    Protein A or Protein G purified

    免疫原

    Human vitronectin purified from plasma by heparin-affinity chromatography

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2-8°C without exposure to light

    有效期

    24 months
  • 抗原

    Vitronectin (VTN)

    别名

    Vitronectin

    背景

    VTN, V75, VN, VNT, vitronectin, complement S-protein, epibolin, serum spreading factor, somatomedin B,Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway., Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.,VTN,Vitronectin is a plasma glycoprotein that circulates in the blood. Vitronectin is circulating as a mixture of both 75 kDa and 65 kDa forms. Vitronectin is a major cell adhesive glycoprotein and is a common component of extracellular matrix and plasma. It competes effectively with other plasma proteins and is often involved in cell attachment, regulation of blood coagulation and immune responses. It has similar tissue distribution to fibronectin and also its integrin receptor recognizes fibronectin. (2)

    分子量

    65 kDa, 75 kDA

    基因ID

    7448

    UniProt

    P04004

    途径

    Autophagy, Smooth Muscle Cell Migration
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