Vitronectin 抗体
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北京 101111
Quick Overview for Vitronectin 抗体 (ABIN8065533)
抗原
See all Vitronectin (VTN) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Anti-Vitronectin Antibody
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特异性
- Vitronectin (human). The epitope is located in the connecting region. Binding can be competed selectively by a peptide comprising aa 121-133.
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预测反应
- Human
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纯化方法
- Protein A or Protein G purified
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免疫原
- Human vitronectin purified from plasma by heparin-affinity chromatography
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亚型
- IgG2b, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C without exposure to light
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有效期
- 24 months
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- Vitronectin (VTN)
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别名
- Vitronectin
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背景
- VTN, V75, VN, VNT, vitronectin, complement S-protein, epibolin, serum spreading factor, somatomedin B,Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway., Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.,VTN,Vitronectin is a plasma glycoprotein that circulates in the blood. Vitronectin is circulating as a mixture of both 75 kDa and 65 kDa forms. Vitronectin is a major cell adhesive glycoprotein and is a common component of extracellular matrix and plasma. It competes effectively with other plasma proteins and is often involved in cell attachment, regulation of blood coagulation and immune responses. It has similar tissue distribution to fibronectin and also its integrin receptor recognizes fibronectin. (2)
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分子量
- 65 kDa, 75 kDA
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基因ID
- 7448
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UniProt
- P04004
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途径
- Autophagy, Smooth Muscle Cell Migration
抗原
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