Adipsin 抗体
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北京 101111
Quick Overview for Adipsin 抗体 (ABIN8065441)
抗原
See all Adipsin (CFD) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Anti-Complement Factor D Antibody
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特异性
- GAU 010-04 is specific for complement factor D in human serum and plasma. Epitope specificity differs from that of GAU 008-01. (1)
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预测反应
- Human
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纯化方法
- Protein A or Protein G purified
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免疫原
- Human factor D
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亚型
- IgG2a, kappa
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anti-Complement Factor D (CFD) (AA 68-99), (N-Term) antibody
CFD 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB19269 unconjugated
anti-Complement Factor D (CFD) (AA 1-253) antibodyCFD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor D (CFD) (AA 1-259) antibodyCFD 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor D (CFD) (AA 26-253) antibodyCFD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor D (CFD) (AA 26-263) antibodyCFD 适用: 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor D (CFD) (AA 26-253) antibodyCFD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor D (CFD) (AA 1-263) antibodyCFD 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor D (CFD) (AA 154-253) antibodyCFD 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F20 unconjugated
anti-Complement Factor D (CFD) (AA 26-253) antibodyCFD 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor D (CFD) (AA 21-120) antibodyCFD 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C without exposure to light
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有效期
- 24 months
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- Adipsin (CFD) (Complement Factor D (CFD))
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别名
- Complement Factor D
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背景
- CFD, ADIPSIN, ADN, DF, PFD, complement factor D, C3 convertase activator, D component of complement (adipsin), complement factor D preproprotein, properdin factor D,Serine protease that initiates the alternative pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system (PubMed:21205667, PubMed:22362762, PubMed:6769474, PubMed:874324, PubMed:9748277). In contrast to other complement pathways (classical, lectin and GZMK) that are directly activated by pathogens or antigen-antibody complexes, the alternative complement pathway is initiated by the spontaneous hydrolysis of complement C3 (PubMed:21205667, PubMed:22362762, PubMed:6769474, PubMed:874324). The alternative complement pathway acts as an amplification loop that enhances complement activation by mediating the formation of C3 and C5 convertases (PubMed:21205667, PubMed:22362762, PubMed:6769474, PubMed:874324). Activated CFD cleaves factor B (CFB) when the latter is complexed with complement C3b, activating the C3 convertase of the alternative pathway (PubMed:21205667, PubMed:6769474, PubMed:874324, PubMed:9748277). {ECO:0000269|PubMed:21205667, ECO:0000269|PubMed:22362762, ECO:0000269|PubMed:6769474, ECO:0000269|PubMed:874324, ECO:0000269|PubMed:9748277}.,CFD,Complement factor D is a serine protease of the alternative pathway of complement activation. The protein is a single chain polypeptide with a molecular mass of 25 kDa. Factor D cleaves factor B bound to C3b, generating the alternative pathway C3 convertase C3bBb and releasing the Ba fragment.
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分子量
- 25 kDa
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基因ID
- 1675
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UniProt
- P00746
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途径
- Complement System
抗原
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