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DDIT3 抗体 (pSer30)

This anti-DDIT3 antibody is a 兔 多克隆 antibody detecting DDIT3 in ELISA, FACS, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人 和 大鼠.
产品编号 ABIN755977
发货至: 中国

Quick Overview for DDIT3 抗体 (pSer30) (ABIN755977)

抗原

See all DDIT3 抗体
DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This DDIT3 antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    pSer30

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Dog,Cow,Sheep,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human GADD153 around the phosphorylation site of Ser30

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

    别名

    GADD153

    背景

    Synonyms: Growth arrest and DNA damage-inducible 153, C/EBP homologous protein, C/EBP Homology Protein, CEBPZ, CHOP 10, CHOP, CHOP10, DDIT 3, DDIT3, DNA Damage Inducible Transcript 3, GADD 153, Growth Arrest and DNA Damage Inducible Protein 153, Growth arrest and DNA damage inducible protein GADD153, MGC4154, DDIT3_HUMAN.

    Background: This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

    基因ID

    1649

    途径

    Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
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