APP 抗体 (pSer730) (Cy7)
Quick Overview for APP 抗体 (pSer730) (Cy7) (ABIN755848)
抗原
See all APP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer730
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human APP770 around the phosphorylation site of Ser730
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亚型
- IgG
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- APP (Amyloid beta (A4) Precursor Protein (APP))
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别名
- Amyloid Precursor Protein
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背景
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Synonyms: Amyloid Precursor Protein phospho S730, Amyloid Precursor Protein phospho Ser730, p-Amyloid Precursor Protein phospho S730, APP Ser730, p-APPSer730, C31, C80, C83, C99, beta-amyloid precursor protein C-terminus, A4 amyloid protein, A4, AAA, ABETA, ABPP, AD 1, AD1, Alzheimer disease 1, Alzheimer disease, Alzheimer's disease amyloid protein, Amyloid beta A4 precursor protein, Amyloid beta A4 protein, Amyloid beta A4 protein precursor isoform b, Amyloid beta A4 protein precursor isoform c, Amyloid beta A4 protein precursor isoform a, Amyloid beta A4 protein precursor isoform b, Amyloid beta A4 protein precursor isoform c, Amyloid beta protein, Amyloid beta-peptide, Amyloid of aging and alzheimer disease, APP, APP I , APPI, Beta amyloid peptide, Cerebral vascular amyloid peptide, CTFgamma, CVAP, Human mRNA for amyloid A4 precursor of Alzheimer's disease, PN 2, PN II, PN2, PreA4, Protease nexin II, A4_HUMAN.
Background: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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基因ID
- 351
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途径
- Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
抗原
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