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ZEB2 抗体 (C-Term) (Fluoro647)

The 兔 多克隆 anti-ZEB2 antibody is suitable to detect ZEB2 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN8055216
发货至: 中国
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Quick Overview for ZEB2 抗体 (C-Term) (Fluoro647) (ABIN8055216)

抗原

See all ZEB2 抗体
ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

适用

  • 80
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人, 小鼠, 大鼠

宿主

  • 77
  • 4
  • 1

克隆类型

  • 77
  • 5
多克隆

标记

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This ZEB2 antibody is conjugated to Fluoro647

应用范围

  • 53
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  • 2
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Flow Cytometry (FACS)
  • 抗原表位

    • 22
    • 12
    • 8
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    • 3
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    C-Term

    原理

    Anti-Smad Interacting Protein 1/ZEB2 Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat,mouse sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human ZEB2, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

    别名

    ZEB2

    背景

    Background: ZEB2 (Zinc finger E-box-binding homeobox2), also known as SIP1or ZINC FINGER HOMEOBOX 1B (ZFHX1B), is a protein that in humans is encoded by the ZEB2 gene. The ZEB2 gene is a member of the ZEB1/Drosophila Zfh1 family of 2-handed zinc finger/homeodomain proteins and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs, the transducers of TGF-beta signaling, and interacts with the nucleosome remodeling and histone deacetylation (NURD) complex. By radiation hybrid analysis, Nagase et al. (1998) mapped the ZEB2 gene to chromosome 2. Wakamatsu et al. (2001) mapped the ZEB2 gene to chromosome 2q22. Vandewalle et al. (2005) showed that expression of mouse Sip1 in human epithelial cells caused a morphologic change from an epithelial to a mesenchymal phenotype. Expression of SNAI1 in epithelial cells triggers an epithelial-mesenchyme transition. Beltran et al. (2008) showed that synthesis of ZEB2 was upregulated following SNAI1 expression in human cell lines.

    Gene Full Name: zinc finger E-box binding homeobox 2

    Sequence Similarities: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

    基因ID

    9839

    UniProt

    O60315

    途径

    Tube Formation
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