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ZEB2 抗体 (AA 1-200) (PE)

The 兔 多克隆 anti-ZEB2 antibody is suitable to detect ZEB2 in samples from 人. It has been validated for FACS.
产品编号 ABIN8055204
发货至: 中国
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Quick Overview for ZEB2 抗体 (AA 1-200) (PE) (ABIN8055204)

抗原

See all ZEB2 抗体
ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

适用

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宿主

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克隆类型

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多克隆

标记

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This ZEB2 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-200

    原理

    Anti-Smad Interacting Protein 1/ZEB2 Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human ZEB2 shares 92% amino acid (aa) sequence identity with mouse ZEB2.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ZEB2 recombinant protein (Position: M1-P200). Human ZEB2 shares 92% amino acid (aa) sequence identity with mouse ZEB2.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

    别名

    ZEB2

    背景

    Background: ZEB2 (Zinc finger E-box-binding homeobox2), also known as SIP1 or ZINC FINGER HOMEOBOX 1B (ZFHX1B), is a protein that in humans is encoded by the ZEB2 gene. The ZEB2 gene is a member of the ZEB1/Drosophila Zfh1 family of 2-handed zinc finger/homeodomain proteins and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs, the transducers of TGF-beta signaling, and interacts with the nucleosome remodeling and histone deacetylation (NURD) complex. By radiation hybrid analysis, this gene is mapped to 2q22. It has been found that synthesis of ZEB2 was upregulated following SNAI1 expression in human cell lines, and the expression of SNAI1 in epithelial cells can trigger an epithelial-mesenchyme transition.

    Gene Full Name: zinc finger E-box binding homeobox 2

    Sequence Similarities: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

    基因ID

    9839

    UniProt

    O60315

    途径

    Tube Formation
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