ZEB2 抗体 (AA 1-200) (PE)
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Quick Overview for ZEB2 抗体 (AA 1-200) (PE) (ABIN8055204)
抗原
See all ZEB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-200
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原理
- Anti-Smad Interacting Protein 1/ZEB2 Antibody PE Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human ZEB2 shares 92% amino acid (aa) sequence identity with mouse ZEB2.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ZEB2 recombinant protein (Position: M1-P200). Human ZEB2 shares 92% amino acid (aa) sequence identity with mouse ZEB2.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))
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别名
- ZEB2
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背景
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Background: ZEB2 (Zinc finger E-box-binding homeobox2), also known as SIP1 or ZINC FINGER HOMEOBOX 1B (ZFHX1B), is a protein that in humans is encoded by the ZEB2 gene. The ZEB2 gene is a member of the ZEB1/Drosophila Zfh1 family of 2-handed zinc finger/homeodomain proteins and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs, the transducers of TGF-beta signaling, and interacts with the nucleosome remodeling and histone deacetylation (NURD) complex. By radiation hybrid analysis, this gene is mapped to 2q22. It has been found that synthesis of ZEB2 was upregulated following SNAI1 expression in human cell lines, and the expression of SNAI1 in epithelial cells can trigger an epithelial-mesenchyme transition.
Gene Full Name: zinc finger E-box binding homeobox 2
Sequence Similarities: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
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基因ID
- 9839
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UniProt
- O60315
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途径
- Tube Formation
抗原
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