WHSC2 抗体 (AA 38-482) (Cy3)
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Quick Overview for WHSC2 抗体 (AA 38-482) (Cy3) (ABIN8054481)
抗原
See all WHSC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 38-482
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原理
- Anti-NELFA Antibody Cy3 Conjugated
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预测反应
- Human NELFA shares 94.6% amino acid (aa) sequence identity with mouse NELFA.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NELFA recombinant protein (Position: I38-L482). Human NELFA shares 94.6% amino acid (aa) sequence identity with mouse NELFA.
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亚型
- IgG
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))
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别名
- NELFA
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背景
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Background: This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93 % sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
Gene Full Name: negative elongation factor complex member A
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基因ID
- 7469
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UniProt
- Q9H3P2
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途径
- Chromatin Binding
抗原
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