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WASP 抗体 (C-Term) (Fluoro488)

The Fluoro488-conjugated 兔 多克隆 anti-WASP antibody (ABIN8054416) specifically detects WASP in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8054416
发货至: 中国
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Quick Overview for WASP 抗体 (C-Term) (Fluoro488) (ABIN8054416)

抗原

See all WASP (WAS) 抗体
WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

适用

  • 94
  • 64
  • 35
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 92
  • 3
  • 1

克隆类型

  • 83
  • 13
多克隆

标记

  • 41
  • 7
  • 7
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This WASP antibody is conjugated to Fluoro488

应用范围

  • 74
  • 39
  • 32
  • 32
  • 17
  • 16
  • 16
  • 13
  • 13
  • 6
  • 3
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 13
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-WASP Antibody Fluoro488 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse sequence by two amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human WASP, different from the related mouse sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

    别名

    WAS

    背景

    Background: The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, ly or inly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.

    Gene Full Name: WASP actin nucleation promoting factor

    Sequence Similarities: Contains 1 CRIB domain.

    基因ID

    7454

    UniProt

    P42768
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