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WASP 抗体 (AA 205-234)

Name: WASP 抗体 (AA 205-234)
SKU: ABIN1881997
Availability: OutOfStock

WAS 适用: 人 WB 宿主: 兔 Polyclonal RB40707 unconjugated

WAS Antibody (Center) (ABIN1881997 and ABIN2838628) western blot analysis in K562 cell line lysates (35 μg/lane). (WASP 抗体 (AA 205-234))

1 image

(3 references)

产品编号 ABIN1881997

发货至: 中国

Datasheet as PDF

抗原 See all WASP (WAS) 抗体

WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
抗原表位
15

14

8

7

7

7

6

6

5

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 205-234
适用
86

55

19

2

1

1

1
人
宿主
83

3

1
兔
Compatible Secondaries
克隆类型
84

3
多克隆
标记
33

8

6

5

4

4

4

4

4

4

3

3

1

1

1

1

1
This WASP antibody is un-conjugated
应用范围
61

37

25

16

13

13

9

5

5

4

4

1

1
Western Blotting (WB)

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This WAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human WAS.

克隆位点

RB40707

亚型

Ig Fraction

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WAS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 129-156), (C-Term) antibody
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anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 60-250) antibody
WAS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 116-144) antibody
WAS 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB23643 unconjugated

anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 122-152), (Middle Region) antibody
WAS 适用: 人, 小鼠 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Almgren, Garamus, Nordstierna, Luc-Blin, Stébé: "Nonideal mixed micelles of fluorinated and hydrogenous surfactants in aqueous solution. NMR and SANS studies of anionic and nonionic systems." in: Langmuir : the ACS journal of surfaces and colloids, Vol. 26, Issue 8, pp. 5355-63, (2010) (PubMed).

Dovas, Gevrey, Grossi, Park, Abou-Kheir, Cox: "Regulation of podosome dynamics by WASp phosphorylation: implication in matrix degradation and chemotaxis in macrophages." in: Journal of cell science, Vol. 122, Issue Pt 21, pp. 3873-82, (2009) (PubMed).

Ameratunga, Woon: "Customised molecular diagnosis of primary immune deficiency disorders in New Zealand: an efficient strategy for a small developed country." in: The New Zealand medical journal, Vol. 122, Issue 1304, pp. 46-53, (2009) (PubMed).
抗原

WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

别名

WAS (WAS 产品)

别名

IMD2 antibody, SCNX antibody, THC antibody, THC1 antibody, WASP antibody, U42471 antibody, WASp antibody, Wasp antibody, imd2 antibody, thc antibody, thc1 antibody, was antibody, wasp antibody, wu:fk81c08 antibody, zgc:64164 antibody, Wiskott-Aldrich syndrome antibody, neural Wiskott-Aldrich syndrome protein antibody, wiskott-aldrich syndrome protein antibody, Wiskott-Aldrich syndrome L homeolog antibody, Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b antibody, WAS antibody, LOC5578888 antibody, CpipJ_CPIJ006699 antibody, Was antibody, was.L antibody, wasb antibody

背景

The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.

分子量

52913

NCBI登录号

NP_000368

UniProt

P42768