VWF 抗体 (AA 1304-1452) (Fluoro488)
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北京 101111
Quick Overview for VWF 抗体 (AA 1304-1452) (Fluoro488) (ABIN8053832)
抗原
See all VWF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1304-1452
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原理
- Anti-Von Willebrand Factor/VWF Antibody Fluoro488 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse VWF recombinant protein (Position: M1304-E1452).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- VWF (Von Willebrand Factor (VWF))
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别名
- VWF
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背景
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Background: Von Willebrand factor (VWF) is a blood glycoprotein involved in hemostasis. It is mapped to 12p13.31. The VWF gene encodes von Willebrand factor (VWF), a large multimeric glycoprotein that plays a central role in the blood coagulation system, serving both as a major mediator of platelet-vessel wall interaction and platelet adhesion, and as a carrier for coagulation factor VIII. VWF released from endothelial cell Weibel-Palade bodies bound particularly avidly to the extracellular matrix. VWF deficiency or dysfunction (von Willebrand disease) leads to a bleeding tendency, which is most apparent in tissues having high blood flow shear in narrow vessels.
Gene Full Name: Von Willebrand factor
Sequence Similarities: Contains 1 CTCK (C-terminal cystine knot-like) domain.
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基因ID
- 22371
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UniProt
- Q8CIZ8
抗原
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