VWF 抗体 (AA 845-949)
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Quick Overview for VWF 抗体 (AA 845-949) (ABIN6940890)
抗原
See all VWF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 845-949
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原理
- von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Antibody
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特异性
- Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human vWF fragment spanning around aa 845-949 (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-Von Willebrand Factor (VWF) (AA 1304-1452) antibody
VWF 适用: 大鼠, 小鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1498-1665) antibodyVWF 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 269-367) antibodyVWF 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 50-150) antibodyVWF 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1815-1939) antibodyVWF 适用: 人 IHC, WB 宿主: 小鼠 Monoclonal VWF-1465 unconjugated
anti-Von Willebrand Factor (VWF) (AA 2535-2813) antibodyVWF 适用: 人 IHC, WB, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) antibodyVWF 适用: 人 IHC, WB, FACS, ELISA 宿主: 小鼠 Monoclonal 907CT12-1-9 unconjugated
anti-Von Willebrand Factor (VWF) (AA 351-450) antibodyVWF 适用: 人, 大鼠, 小鼠 FACS, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 49-230) antibodyVWF 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1-273) antibodyVWF 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A11 unconjugated
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应用备注
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Positive Control: HUVEC cells. Tonsil.
Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunoprecipitation (1-2 μg/500 μg protein lysate),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- VWF (Von Willebrand Factor (VWF))
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别名
- VWF
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背景
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Coagulation Factor VIII, Factor VIII Related Antigen, F8VWF, von Willebrand Antigen 2, von Willebrand Disease (vWD)
HUVEC cells. Human tonsil.
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分子量
- 250kDa
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基因ID
- 7450, 440848
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UniProt
- P04275
抗原
-
