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VRK1 抗体 (C-Term) (APC)

This 兔 多克隆 antibody specifically detects VRK1 in FACS. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN8053199
发货至: 中国
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Quick Overview for VRK1 抗体 (C-Term) (APC) (ABIN8053199)

抗原

See all VRK1 抗体
VRK1 (Vaccinia Related Kinase 1 (VRK1))

适用

  • 61
  • 12
  • 10
人, 大鼠

宿主

  • 52
  • 9

克隆类型

  • 54
  • 7
多克隆

标记

  • 27
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This VRK1 antibody is conjugated to APC

应用范围

  • 46
  • 18
  • 13
  • 13
  • 9
  • 8
  • 8
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 11
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-VRK1 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    different from the related mouse sequence by three amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human VRK1, different from the related mouse sequence by three amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    VRK1 (Vaccinia Related Kinase 1 (VRK1))

    别名

    VRK1

    背景

    Background: Serine/threonine-protein kinase VRK1 is an enzyme that in humans is encoded by the VRK1 gene. This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. It is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

    Gene Full Name: VRK serine/threonine kinase 1

    基因ID

    7443

    UniProt

    Q99986
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