UPF3B 抗体 (C-Term) (Cy3)
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Quick Overview for UPF3B 抗体 (C-Term) (Cy3) (ABIN8052885)
抗原
See all UPF3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-UPF3B/RENT3B Antibody Cy3 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human UPF3B /RENT3B.
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亚型
- IgG
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anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (C-Term) antibody
UPF3B 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (AA 319-423) antibodyUPF3B 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) antibodyUPF3B 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (N-Term) antibodyUPF3B 适用: 人, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (AA 252-301) antibodyUPF3B 适用: 人, 犬, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (N-Term) antibodyUPF3B 适用: 人, 小鼠, 大鼠, 犬, 兔, Pig, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
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别名
- UPF3B
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背景
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Background: Regulator of nonsense transcripts 3B is a protein that in humans is encoded by the UPF3B gene. This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene.
Gene Full Name: UPF3B regulator of nonsense mediated mRNA decay
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基因ID
- 65109
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UniProt
- Q9BZI7
抗原
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