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RENT2/UPF2 抗体 (AA 200-651) (HRP)

The HRP-conjugated 兔 多克隆 anti-RENT2/UPF2 antibody (ABIN8052868) specifically detects RENT2/UPF2 in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN8052868
发货至: 中国
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Quick Overview for RENT2/UPF2 抗体 (AA 200-651) (HRP) (ABIN8052868)

抗原

See all RENT2/UPF2 (UPF2) 抗体
RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

适用

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宿主

  • 29

克隆类型

  • 29
多克隆

标记

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This RENT2/UPF2 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 200-651

    原理

    Anti-hUPF2/RENT2/UPF2 Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human hUPF2/RENT2/UPF2 recombinant protein (Position: K200-H651).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

    别名

    UPF2

    背景

    Background: Regulator of nonsense transcripts 2 is a protein that in humans is encoded by the UPF2 gene. This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein.

    Gene Full Name: UPF2 regulator of nonsense mediated mRNA decay

    基因ID

    26019

    UniProt

    Q9HAU5
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