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TDP1 抗体 (AA 1-499) (Fluoro488)

The Fluoro488-conjugated 兔 多克隆 anti-TDP1 antibody (ABIN8051866) specifically detects TDP1 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8051866
发货至: 中国
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Quick Overview for TDP1 抗体 (AA 1-499) (Fluoro488) (ABIN8051866)

抗原

See all TDP1 抗体
TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

适用

  • 51
  • 29
  • 19
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 44
  • 8
  • 1

克隆类型

  • 47
  • 6
多克隆

标记

  • 35
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
This TDP1 antibody is conjugated to Fluoro488

应用范围

  • 39
  • 23
  • 16
  • 15
  • 12
  • 9
  • 7
  • 3
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 12
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-499

    原理

    Anti-TDP1 Antibody Fluoro488 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human TDP1 shares 78.8%,79.6% amino acid (aa) sequence identity with mouse,rat TDP1,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TDP1 recombinant protein (Position: M1-R499). Human TDP1 shares 78.8% and 79.6% amino acid (aa) sequence identity with mouse and rat TDP1, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

    别名

    TDP1

    背景

    Background: The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1).

    Gene Full Name: tyrosyl-DNA phosphodiesterase 1

    基因ID

    55775

    UniProt

    Q9NUW8
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