TP53I3 抗体 (AA 1-332) (PE)
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北京 101111
Quick Overview for TP53I3 抗体 (AA 1-332) (PE) (ABIN8051641)
抗原
See all TP53I3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-332
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原理
- Anti-PIG3/TP53I3 Antibody PE Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PIG3/TP53I3 recombinant protein (Position: M1-Q332).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
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别名
- TP53I3
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背景
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Background: Putative quinone oxidoreductase is an enzyme that in humans is encoded by the TP53I3 gene. The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats ly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: tumor protein p53 inducible protein 3
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基因ID
- 9540
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UniProt
- Q53FA7
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途径
- p53 Pathway
抗原
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