STRAP 抗体 (AA 51-150)
-
- 抗原 See all STRAP 抗体
- STRAP (Serine/threonine Kinase Receptor Associated Protein (STRAP))
-
抗原表位
- AA 51-150
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This STRAP antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Cow,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Unrip
- 亚型
- IgG
- Top Product
- Discover our top product STRAP Primary Antibody
-
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 1-350) antibody
STRAP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 242-269), (C-Term) antibodySTRAP 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20860 unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (N-Term) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 101-150) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, 斑马鱼, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) antibodySTRAP 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 281-330) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 78-104), (N-Term) antibodySTRAP 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (C-Term) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- STRAP (Serine/threonine Kinase Receptor Associated Protein (STRAP))
- 别名
- Unrip (STRAP 产品)
- 别名
- MAWD antibody, PT-WD antibody, UNRIP antibody, zgc:56677 antibody, zgc:77604 antibody, mawd antibody, pt-wd antibody, unrip antibody, AW557906 antibody, C78091 antibody, C79202 antibody, Unrip antibody, serine/threonine kinase receptor associated protein antibody, tetratricopeptide repeat domain 5 antibody, serine/threonine kinase receptor associated protein L homeolog antibody, serine/threonine kinase receptor associated protein S homeolog antibody, STRAP antibody, TTC5 antibody, strap antibody, strap.L antibody, strap.S antibody, Strap antibody
- 背景
-
Synonyms: MAP activator with WD repeats, MAWD, PTWD, serine/threonine kinase receptor associated protein, STRAP, UNR-interacting protein, UNRIP, WD 40 repeat protein PT WD, STRAP_HUMAN.
Background: Unrip is part of the SMN complex that plays a role in snRNP assembly in the cytoplasm and pre mRNA splicing in the nucleus. Unrip interacts directly with Gemin 6 and Gemin 7 in the SMN complex. It is associated with the complex in the cytoplasm but not in the nucleus and thus is thought to play a role in it's subcellular localisation.It is a ubiquitously expressed protein that acts as an inhibitor of TGF-beta signaling and an important regulator of cell proliferation. Stable expression of STRAP results in activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway and in down-regulation of the cyclin-dependent kinase inhibitor p21 (Cip1), which results in retinoblastoma protein hyperphosphorylation. Upregulation of STRAP might play a role in tumor development as an early event for colorectal cancers. It is the first component of the U snRNP assembly machinery that associates with SMN complex in a compartment-specific way and plays a crucial role in the intracellular distribution of SMN1.
- 基因ID
- 11171
-
