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- 抗原 See all STRAP 抗体
- STRAP (Serine/threonine Kinase Receptor Associated Protein (STRAP))
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抗原表位
- AA 1-350
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STRAP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Serine-threonine kinase receptor-associated protein (1-350AA)
- 亚型
- IgG
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anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 242-269), (C-Term) antibody
STRAP 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20860 unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (N-Term) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 101-150) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, 斑马鱼, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) antibodySTRAP 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 281-330) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 78-104), (N-Term) antibodySTRAP 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (C-Term) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- STRAP (Serine/threonine Kinase Receptor Associated Protein (STRAP))
- 别名
- STRAP (STRAP 产品)
- 别名
- MAWD antibody, PT-WD antibody, UNRIP antibody, zgc:56677 antibody, zgc:77604 antibody, mawd antibody, pt-wd antibody, unrip antibody, AW557906 antibody, C78091 antibody, C79202 antibody, Unrip antibody, serine/threonine kinase receptor associated protein antibody, tetratricopeptide repeat domain 5 antibody, serine/threonine kinase receptor associated protein L homeolog antibody, serine/threonine kinase receptor associated protein S homeolog antibody, STRAP antibody, TTC5 antibody, strap antibody, strap.L antibody, strap.S antibody, Strap antibody
- 背景
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Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. STRAP plays a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein.
Aliases: MAP activator with WD repeats antibody, MAWD antibody, PTWD antibody, Serine-threonine kinase receptor-associated protein antibody, serine/threonine kinase receptor associated protein antibody, strap antibody, STRAP_HUMAN antibody, UNR-interacting protein antibody, UNRIP antibody, WD 40 repeat protein PT WD antibody, WD-40 repeat protein PT-WD antibody
- UniProt
- Q9Y3F4
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