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TFF1 抗体 (AA 25-84) (APC)

This 兔 多克隆 antibody specifically detects TFF1 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN8049347
发货至: 中国
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Quick Overview for TFF1 抗体 (AA 25-84) (APC) (ABIN8049347)

抗原

See all TFF1 抗体
TFF1 (Trefoil Factor 1 (TFF1))

适用

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宿主

  • 137
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克隆类型

  • 111
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多克隆

标记

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This TFF1 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 25-84

    原理

    Anti-Estrogen Inducible Protein pS2/TFF1 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    coli-derived human TFF1 recombinant protein (Position: E25-F84). Human TFF1 shares 66.7%,69% amino acid (aa) sequence identity with mouse,rat TFF1,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human TFF1 recombinant protein (Position: E25-F84). Human TFF1 shares 66.7% and 69% amino acid (aa) sequence identity with mouse and rat TFF1, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    TFF1 (Trefoil Factor 1 (TFF1))

    别名

    TFF1

    背景

    Background: TFF1 (Trefoil factor 1), also known as pS2, is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. It is found that TFF1 in normal human urine inhibited the growth of calcium oxalate crystals. Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by TFF1 antisera, particularly by antisera ed to the TFF1 C terminus. Concentrations and relative amounts of TFF1 in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

    Gene Full Name: trefoil factor 1

    Sequence Similarities: Contains 1 P-type (trefoil) domain.

    基因ID

    7031

    UniProt

    P04155

    途径

    EGFR Signaling Pathway
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